Seeking a seasoned scientific professional who is proficient with all facets of downstream protein manufacturing from pilot to production scale and who is ready to transition into hands on leadership role
Requires 4+ years experience developing purification processes for proteins, enzymes, PEGylated proteins, antibodies, or peptides to be scaled up and transferred from development to clinical and commercial manufacturing.
Join a company focused on the future. Offering extremely generous ...
Seeking experience developing methods for characterization of protein drug candidates, hands on development experience with Liquid chromatography - Mass Spectrometry, two dimensional Gel Electrophoresis, and track record contributing to BLA and IND filings to lead group of 4 scientists supporting process development and final product comparability evaluations for vaccine developer and manufacturer.
World class vaccine development and manufacturing company offering an amazing opportunity to lead a ...
Position Title: Sr Associate Scientist, Technical Development in Cambridge, MA.
This position is for a senior associate scientist contractor within Analytical Development. The employee will perform analytical method development and protein characterization using analytical techniques such as liquid chromatography and mass spectrometry to support product development. The candidate should have experience in analysis of protein molecules using mass spectrometry techniques. Relevant ...
The Structural Biophysics Group at the Novartis Institutes for BioMedical Research is looking for a talented and highly motivated scientist to assume a hands-on role in the use biophysical methods to characterize proteins, protein complexes and their interactions with small molecules. The candidate will actively participate in experimental design, performing experiments, and troubleshooting, as well as, performing data analysis and interpretation. The ideal candidate will be ...
• The person in this function will be responsible for developing purification processes for manufacturing novel viral vaccine candidates for toxicology studies and Phase I/II/III clinical trials.
• Execute experiments in close collaboration with Research and Technology Development team to establish Phase I-III clinical manufacturing process
• Perform activities in support of definition of bulk purification processes for novel viral vaccine candidates (virus/virus-like particles, ...
Seeking expert knowledge of assay design and execution specifically for cell based assays, biochemical assays, and histological tests as well as a documented history of effective leadership in a drug discovery environment to lead a small scientific team focused on identifying and evaluating gene expressed proteins or peptides acting as renal biomarkers.
PhD relevant field and at least 4 years similar experience required.
Advance rapidly in this highly visible position. Top compensation package ...
Major developer of novel renal therapeutics seeks 3+ years experience and strong working knowledge of in vivo pharmacology techniques to:
*** Prepare test compounds
*** Handle and dose mice
*** Collect blood and tissue samples for PK and PD biomarker analysis
*** Establish PK-PD relationships from in vivo assays
*** Generate human dose predictions for clinical development
*** Assess the mechanism of action and therapeutic viability for novel renal therapies
PhD Life Sciences, ...
Seeking Ph.D. or M.D. and 10+ years in pre-clinical drug discovery and development for autoimmune, inflammation or respiratory therapeutic target entities including the development of in vivo, in vitro and ex vivo evaluation models.
*** Participate in selection of specific protein & antibody entities as novel targets or drug leads for therapeutic consideration and develop research strategy.
*** Supervise development of in vivo, in vitro and ex vivo evaluation models.
*** Oversee ...
Seeking a scientific leader to oversee the development of preclinical models of inflammatory diseases to support clinical development collaborations, based on the pathophysiology of disease and the mechanism of action of drugs.
*** Prepare, initiate, and manage all preclinical research studies
*** Establish collaborations with pharmaceutical and academic organizations
*** Manage a team of up to 10 Scientists
Candidate must have 10+ years similar experience and possess PhD in Biology, ...
Special Order Notes:
1.) Protein structural chemistry - characterization of protein variance
Biophysical type candidate
2.) Analytical methods
3.) Enzyme structure function / Biophysical methods
Forced degradation studies (how the molecules break apart)
Class of molecules in important and mechanisms of them.
Reverse Phase Chromotography
(No enzyme assay development)
Job Title: Postdoctoral Scientist
Seeking Ph.D. and experience managing Assay Development Groups identifying targets, and developing and validating new immunoassay products.
*** Antibody selection
*** Assay development
*** Transfer to manufacturing
*** Documentation development.
*** Recombinant Proteins.
*** Antibody Development.
This company is poised for tremendous growth in the near future. This leadership opportunity comes with and incredible starting ...
our client is looking for an associate scientist in cambridge, ma. this is a long term position.
Job Description We are seeking motivated and creative individuals to join our Cell Line Development team through April 2013 and contribute to ongoing efforts to engineering superior host cell lines for the manufacturing of therapeutic proteins. The successful candidate will have mammalian cell culture/cell line development experience. Candidates with experience performing transfections, basic molecular ...
Our client, a top biotechnology company, is looking for an Associate Scientist (Formulation Development). This is a one year contract opportunity in Cambridge, MA.
We are looking for a contract Associate Scientist to join our Protein Pharmaceutical Development Department. The successful candidate will assist in protein formulation development activities to support preclinical, clinical and commercial drug development teams.
The candidate will be responsible for supporting protein ...
Mar 21 -
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