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  1. Oncologist - Molecular Biomarker Strategies - Boston, MA

    Provide strategic leadership for teams focused on the development of personalized medicine based on the discovery of molecular biomarkers. Utilizing patient derived data from genomic and molecular analyses you will develop strategies to drive oncology therapeutics through the clinic Shall: *** Work with clinicians and laboratories to develop novel biomarkers, research tools and study designs derived from the safety, pharmacokinetic and pharmacodynamic data obtain in the early phase trials. *** ...

  2. 3698326 – Clinical Trial Head

    Description: Accountable for all aspects of assigned OTM clinical trials (Phase I/II) including leading Clinical Trial Team(s) (CTT). Number of clinical trials depends on the workload and complexity of the individual trials. Responsible for program level activities as assigned. Responsibilities: • Lead the clinical protocol development process in collaboration with the Clinical Program Leader (CPL): responsible author for clinical protocols, amendments and related documents; contribute to the medical ...

  3. 3697177 – Clinical Trial Leader II

    Description: Accountable for all aspects of assigned OTM clinical trials (Phase I/II) including leading Clinical Trial Team(s) (CTT). Number of clinical trials depends on the workload and complexity of the individual trials. Responsible for program level activities as assigned. Responsibilities: • Lead the clinical protocol development process in collaboration with the Clinical Program Leader (CPL): responsible author for clinical protocols, amendments and related documents; contribute to the ...

  4. 3707720 – Biomarker Trial Head

    Description: Support the operational execution of the clinical study strategies related to biomarker and pharmacokinetic assessments in oncology protocols, in compliance with client’s processes and regulatory requirements and in collaboration with Oncology Clinical Teams. Responsibilities: • Sample tracking for biomarker and pharmacokinetic samples from clinical site to analytical laboratory. • This includes setting up the laboratory procedures, being the primary point of contact and providing ...

  5. Director Clinical Data Integration - Molecular Biomarker Discovery

    We are looking for a highly motivated senior level Director to work closely with key clinical personnel to optimize preclinical strategies focused on pharmacodynamic and predictive biomarkers. Shall: *** Generate strategies utilizing your expertise in cancer signaling pathway biology *** Drive the discovery of biomarkers related to molecular mechanism of action, pharmacodynamics and predictors of resistance pathways *** Provide scientific expertise to teams developing biomarker assays ...

  6. Sr. Director Molecular Strategies - Clinical Immuno-Oncology - Boston

    We are seeking a dynamic thought leader in oncology to develop pre-clinical biomarker strategies derived from clinical data analysis. You will provide scientific and strategic leadership to support oncology molecules in all phases of development. Shall: *** Oversee the development of biomarker strategies and ensure successful execution of drug-diagnostic development *** Leverage your expertise to drive the publication of biomarker data in high quality scientific, technical, and medical ...

  7. Group Leader – Target Discovery - Chronic Kidney Disease

    Seeking expert knowledge of assay design and execution specifically for cell based assays, biochemical assays, and histological tests as well as a documented history of effective leadership in a drug discovery environment to lead a small scientific team focused on identifying and evaluating gene expressed proteins or peptides acting as renal biomarkers. PhD relevant field and at least 4 years similar experience required. Advance rapidly in this highly visible position. Top compensation package ...

  8. Scientist - Renal In Vivo Pharmacology - Cambridge, MA

    Major developer of novel renal therapeutics seeks 3+ years experience and strong working knowledge of in vivo pharmacology techniques to: *** Prepare test compounds *** Handle and dose mice *** Collect blood and tissue samples for PK and PD biomarker analysis *** Establish PK-PD relationships from in vivo assays *** Generate human dose predictions for clinical development *** Assess the mechanism of action and therapeutic viability for novel renal therapies PhD Life Sciences, ...

  9. Senior Director Drug Discovery - Cambridge, MA

    Seeking Ph.D. or M.D. and 10+ years in pre-clinical drug discovery and development for autoimmune, inflammation or respiratory therapeutic target entities including the development of in vivo, in vitro and ex vivo evaluation models. Shall: *** Participate in selection of specific protein & antibody entities as novel targets or drug leads for therapeutic consideration and develop research strategy. *** Supervise development of in vivo, in vitro and ex vivo evaluation models. *** Oversee ...

  10. Senior Director - Inflammation - Boston, MA

    Seeking a scientific leader to oversee the development of preclinical models of inflammatory diseases to support clinical development collaborations, based on the pathophysiology of disease and the mechanism of action of drugs. Shall: *** Prepare, initiate, and manage all preclinical research studies *** Establish collaborations with pharmaceutical and academic organizations *** Manage a team of up to 10 Scientists Candidate must have 10+ years similar experience and possess PhD in Biology, ...

  11. Director of Assay Developemnt Group - Woburn, MA

    Lead team focused on the development, validation, and implementation of multi-modal assays that test for disparate target types, including miRNAs, single-nucleotide polymorphisms, gene expression biomarkers, and hybrid genes caused by translocation, interstitial deletion, or chromosomal inversion. Hands-on role in developing assays, validation, and managing the transfer to manufacturing. Highly visible director level position with a leader in the scientific community. Salary $100,000 to $140,000 ...

  12. Assay Development Project Manager - Framingham, MA

    Seeking Ph.D. and experience managing Assay Development Groups identifying targets, and developing and validating new immunoassay products. Shall oversee: *** Antibody selection *** Assay development *** Transfer to manufacturing *** Documentation development. Required Experience: *** Recombinant Proteins. *** Antibody Development. *** Multiplexing. This company is poised for tremendous growth in the near future. This leadership opportunity comes with and incredible starting ...